4.8 Article

Graphene oxide for rapid microRNA detection

Journal

NANOSCALE
Volume 4, Issue 19, Pages 5840-5842

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2nr31497e

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Funding

  1. 973 Program [2010CB933903]
  2. Hunan Provincial Natural Science Foundation of China [12JJ4049]
  3. Open Research Fund of State Key Laboratory of Bioelectronics, Southeast University [2011E27]
  4. China Postdoctoral Science Foundation [2012M511660]

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We have developed a fluorescence quenching based approach using graphene oxide (GO) for rapid detection of miRNAs. This GO-based method has been demonstrated to be highly specific to homogenous miRNAs, and is reverse transcription free which simplifies the detection procedures and reduces the total analysis time and cost.

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