Paramagnetic nanofibrous composite films enhance the osteogenic responses of pre-osteoblast cells

In this work, a paramagnetic nanofibrous composite film was fabricated with poly lactide, hydroxyapatite and gamma-Fe(2)0(3); nanoparticles using the electrospinning technique. The composite film significantly enhanced the proliferation, differentiation and ECM secretion of the osteoblast cells under a static magnetic field, which offers promising application potentials in bone tissue engineering and bone regeneration therapy.