Journal
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
Volume 5, Issue 4, Pages 387-393Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.nano.2009.01.011
Keywords
Nano-Cancer therapy; Nanotherapy; Brain tumor; Nanoethics; Magnetic fluid hyperthermia; Glioblastoma multiforme
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This paper describes the worldwide first nanoparticle-based therapy against brain tumors termed magnetic fluid hyperthermia (MFH) or Nano-Cancer therapy, which now is under investigation in a phase II study. The preliminary results show evidence of a local effectiveness and with only minor to moderate therapy-associated side effects. The evaluation, according to the principles of medical ethics (autonomy, beneficence, nonmaleficence, justice), supports the further development of the MFH therapy. From the Clinical Editor: This paper describes the worlwide first nanoparticle-based therapy of brain tumors through local hyperthermia now under investigation in a phase II study. The preliminary results show effectiveness and only minor to moderate side effects. Further development of this novel therapy is justified. (C) 2009 Elsevier Inc. All rights reserved.
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