Journal
NANOMEDICINE
Volume 6, Issue 1, Pages 111-122Publisher
FUTURE MEDICINE LTD
DOI: 10.2217/NNM.10.141
Keywords
drug delivery; elastin-like recombinamers; nanodevices; protein purification; surface engineering; tissue engineering
Funding
- EU
- Ministerio de Ciencia e Innovacion - Inoicio (MICINN) [MAT 2007-66275-C02-01, MAT 2007-61604, MAT 2009-14195-C03-03, PSE-300100-2006-2001]
- Junta de Castilla y Leon (JCyL) [VA034A09, VA030A08]
- El Centro de Investigacion Biomedica en Red en Bioingenieria, Biomateriales y Nanomedicina [CB06-01-0003]
- Instituto de Salud Carlos III under the 'Network Center of Regenerative Medicine and Cellular Therapy of Castilla and Leon'
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Elastin-like recombinamers have grown in popularity in the field of protein-inspired biomimetic materials and have found widespread use in biomedical applications. Modern genetic-engineering techniques have allowed the design of multifunctional materials with an extraordinary control over their architecture and physicochemical properties, such as stimuli-responsiveness, monodispersity, biocompatibility or self-assembly, amongst others. Indeed, these materials are playing an increasingly important role in a diverse range of applications, such as drug delivery, tissue engineering and 'smart' systems. Herein, we review some of the most interesting examples of recent advances, and progressive applications of elastin-like recombinamers in biomaterial and nano-engineering sciences in recent years.
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