Journal
NANO RESEARCH
Volume 11, Issue 10, Pages 5372-5399Publisher
TSINGHUA UNIV PRESS
DOI: 10.1007/s12274-018-2189-3
Keywords
nanomaterial; neuron; cardiomyocyte; nanoelectronics; bioelectronics; hybrid tissue
Categories
Funding
- China Research Council Award [[2016]3100]
- National Defense Science and Engineering Graduate Fellowship
- Tufts Collaborates Award
Ask authors/readers for more resources
Solid-state nanomaterials exhibit complementary interactions with biological systems because of their biologically-relevant size scales and rationally tunable electrical, chemical and mechanical properties. In this review, we focus specifically on one-dimensional (1D) nanomaterials such as silicon or gold nanowires or carbon nanotubes. We discuss the nature of the nanomaterial-cell interface, and how that interface may be engineered to enhance or modulate cellular function. We then describe how those unique interfaces may be exploited in three-dimensional (3D) tissue culture to recapitulate the extracellular matrix and promote or complement morphogenesis. Finally, we describe how 1D nanomaterials may be elucidated as nanoelectronic devices that monitor the chemical or electrical environment of cells or tissue with exquisite spatial and temporal resolution. We discuss prospects for entirely new classes of engineered, hybrid tissues with rationally-designed biological function and two-way, closed-loop electronic communication.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available