Journal
NANO LETTERS
Volume 15, Issue 1, Pages 770-775Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nl504497m
Keywords
Nanoparticles; optical force; plasmonic heating; nanoinjection
Categories
Funding
- ERC
- DFG [SFB 1032]
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The controlled injection of nanoscopic objects into living cells with light offers promising prospects for the development of novel molecular delivery strategies or intracellular biosensor applications. Here, we show that single gold nanoparticles from solution can be patterned on the surface of living cells with a continuous wave laser beam. In a second step, we demonstrate how the same particles can then be injected into the cells through a combination of plasmonic heating and optical force. We find that short exposure times are sufficient to perforate the cell membrane and inject the particles into cells with a survival rate of >70%.
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