4.8 Article

Transporting a Tube in a Tube

Journal

NANO LETTERS
Volume 14, Issue 11, Pages 6160-6164

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/nl502316a

Keywords

LbL-assembly; nanotube; kinesin; microtubule; unidirectional movement

Funding

  1. National Nature Science Foundation of China [91027045, 21320102004, 21321063, 21303221]
  2. National Basic Research Program of China (973 program) [2013CB932800]

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LbL-assembled tubes were employed for micro/nanoscale cargo transportation through the kinesin-microtubule system. Selectively modified with kinesins onto the inner tube walls through Ni-NTA complexes, these tubes can work as channels for microtubules. A motility assay shows the smooth movement of microtubules along the tube inner wall powered by the inside immobilized kinesins. It could be envisioned that cargoes with different sizes can be transported through these tubular channels with little outside interruption.

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