Journal
NANO LETTERS
Volume 13, Issue 6, Pages 2864-2869Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nl401205b
Keywords
Nanowires; bacteria; diffusion; single-cell imaging; trajectory analysis
Categories
Funding
- National Science Foundation
- National Research Foundation of Korea [2012R1A2A1A03010558]
- Pioneer Research Program for Converging Technology [2009-008-1529]
- National Research Foundation of Korea [2012R1A2A1A03010558] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Ask authors/readers for more resources
Understanding how living cells interact with nanostructures is integral to a better understanding of the fundamental principles of biology and the development of next generation biomedical/bioenergy devices. Recent studies have demonstrated that mammalian cells can recognize nanoscale topographies and respond to these structures. From this perspective, there is a growing recognition that nanostructures, along with their specific physicochemical properties, can also be used to regulate the responses and motions of bacterial cells. Here, by utilizing a well-defined silicon nanowire array platform and single-cell imaging, we present direct evidence that Shewanella oneidensis MR-1 can recognize nanoscale structures and that their swimming patterns and initial attachment locations are strongly influenced by the presence of nanowires on a surface. Analyses of bacterial trajectories revealed that MR-1 cells exhibited a confined diffusion mode in the presence of nanowires and showed preferential attachment to the nanowires, whereas a superdiffusion mode was observed in the absence of nanowires. These results demonstrate that nanoscale topography can affect bacterial movement and attachment and play an important role during the early stages of biofilm formation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available