Journal
NANO LETTERS
Volume 12, Issue 3, Pages 1638-1642Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nl2045759
Keywords
Si nanowire; RTCVD; gold nanocluster; breast cancer cells; photothermal therapy
Categories
Funding
- Star Faculty Program [KRF-2005-084-000017]
- Center for Multiscale Energy System
- World Class University Program [R31-2009-100320]
- National Research Foundation of Korea
- National Research Foundation of Korea (NRF)
- Ministry of Education, Science, and Technology [2011-00125]
Ask authors/readers for more resources
We report on rapid thermal chemical vapor deposition growth of silicon nanowires (Si NWs) that contain a high density of gold nanoclusters (Au NCs) with a uniform coverage over the entire length of the nanowire sidewalls. The Au NC-coated Si NWs with an antibody-coated surface obtain the unique capability to capture breast cancer cells at twice the highest efficiency currently achievable (similar to 88% at 40 min cell incubation time) from a nanostructured substrate. We also found that irradiation of breast cancer cells captured on Au NC-coated Si NWs with a near-infrared light resulted in a high mortality rate of these cancer cells, raising a fine prospect for simultaneous capture and plasmonic photothermal therapy for circulating tumor cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available