Journal
NANO LETTERS
Volume 12, Issue 6, Pages 3290-3295Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nl301399z
Keywords
Dynamic DNA nanotechnology; strand displacement; reconfiguration; fractal
Categories
Funding
- ONR
- NSF
- ARO
- DOE
- NIH
- Sloan Research Foundation
- NSFC [21028005]
- Wong Kwan Cheng education foundation
- Direct For Computer & Info Scie & Enginr
- Division of Computing and Communication Foundations [0829685] Funding Source: National Science Foundation
- Direct For Mathematical & Physical Scien
- Division Of Materials Research [1104373] Funding Source: National Science Foundation
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The specificity of Watson Crick base pairing, unique mechanical properties of DNA, and intrinsic stability of DNA double helices makes DNA an ideal material for the construction of dynamic nanodevices. Rationally designed strand displacement reactions can be used to produce dynamic reconfiguration of DNA nanostructures postassembly. Here we describe a 'fold-release-fold' strategy of multiple strand displacement and hybridization reactions to reconfigure a simple DNA origami structure into a complex, quasifractal pattern, demonstrating a complex transformation of DNA nanoarchitectures.
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