Journal
NANO LETTERS
Volume 10, Issue 12, Pages 4858-4862Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nl1025826
Keywords
Nanowires; phage display; PEDOT; biosensing; conducting polymers
Categories
Funding
- National Science Foundation [CHE-0956524]
- NAID [1 R43 AI074163]
- NCI of the National Institutes of Health [R01 CA133592-01]
- Direct For Mathematical & Physical Scien [0956524] Funding Source: National Science Foundation
- Division Of Chemistry [0956524] Funding Source: National Science Foundation
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The separate fields of conducting polymer based electrochemical sensors and virus based molecular recognition offer; numerous advantages for biosensing Grafting M13 bacteriophage into an array of poly (3 4 ethylenedioxythlophene) (PEDOT) nanowires generated hybrids of conducting polymers and viruses The virus incorporation into the polymeric backbone of PEDOT occurs during electropolymerization via lithographically patterned nanowire electrodeposition The resultant arrays of virus PEDOT nanowires enable real time reagent free electrochemical biosensing of analytes in physiologically relevant buffers
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