4.8 Article

Endosomal Leakage and Nuclear Translocation of Multiwalled Carbon Nanotubes: Developing a Model for Cell Uptake

Journal

NANO LETTERS
Volume 9, Issue 12, Pages 4370-4375

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/nl902647x

Keywords

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Funding

  1. National Cancer Institute [P30CA027165]
  2. American Lebanese Syrian Associated Charities (ALSAC)
  3. St. Jude Children's Research Hospital

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We report our findings on cellular membrane penetration, endocytosis, endosomal leakage, and nuclear translocation of multiwalled carbon nanotubes (MWCNTs). Our data is consistent with a working model for MWCNTs' cell uptake and cellular translocations.

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