Journal
NANO LETTERS
Volume 8, Issue 10, Pages 3450-3455Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nl802317d
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- ETH Zurich
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Single binding events of nanoparticle-labeled DNA strands were detected as stepwise peak shifts in localized surface plasmon resonance by single particle measurement. We confirmed the number of binding events by observing label particles by scanning electron microscopy. Our simulation based on a multiple multipole program showed that the peak shift is dependent on interparticle gap size and binding position. The experimental peak shift distribution was also reproduced by simulation.
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