Journal
NANO LETTERS
Volume 8, Issue 9, Pages 2659-2663Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nl800914m
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Funding
- French ANR
- ESRF
- Assistance Publique-Hopitaux de Paris
- C'nano IdF
- CNRS
- CEA
- MESR
- Region Ile-de-France
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X-ray fluorescence microscopy (mu XRF) is applied for the first time to study macrophages exposed to unpurified and purified single-walled (SW) and multiwalled (MW) carbon nanotubes (CNT). Investigating chemical elemental distributions allows one to (I) image nanotube localization within a cell and (ii) detect chemical modification of the cell after CNT internalization. An excess of calcium is detected for cells exposed to unpurified SWCNT and MWCNT and related toxicological assays are discussed.
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