Journal
MYCOSES
Volume 54, Issue 4, Pages E57-E61Publisher
WILEY
DOI: 10.1111/j.1439-0507.2009.01833.x
Keywords
Candida albicans; Candida africana; Candida biofilm; human Hela cells; HWP1 gene
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In this study, we compared the adherence ability to human Hela cells and biofilm formation of three closely related Candida yeast. In our experiments, Candida africana showed poor adhesion ability to human Hela cells and the absence of biofilm formation on polyvinyl chloride strips. Conversely, Candida albicans and Candida dubliniensis formed mature biofilms and stable attachment to Hela cells. To our knowledge, this is the first comparative study reporting data on biofilm formation and adherence to human Hela cells by C. africana.
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