Journal
SENSORS
Volume 15, Issue 12, Pages 31987-31998Publisher
MDPI AG
DOI: 10.3390/s151229902
Keywords
3-(4-diethylaminocinnamoyl) coumarins; fluorescence; DCP; nerve gas sensors; two-photon fluorescence
Funding
- DU-DST Purse Grant II
- University of Delhi
- Council of Scientific and Industrial Research (CSIR, New Delhi)
- Erasmas NAMASTE consortium grant [NAMASTE_20130125]
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We have synthesized two novel fluorescent 3-(4-diethylaminocinnamoyl) coumarins that exhibit fluorescence quenching upon exposure to a nerve agent simulant, diethylchlorophosphate (DCP), providing a basis for rapid and sensitive DCP chemosensing. Furthermore, these coumarin derivatives display two-photon fluorescence upon illumination with near-infrared laser pulses and their two-photon (TP) absorption cross-section was evaluated. The potential for TP bio-imaging of these compounds was investigated by their cellular uptake in HeLa cells by TP confocal microscopy.
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