Journal
MYCOLOGICAL PROGRESS
Volume 11, Issue 3, Pages 599-614Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s11557-012-0825-y
Keywords
Cultivation; Entomopathogenic fungus; Mating system; Pharmaceutical application
Categories
Funding
- Green Energy Mission/Nepal, Kathmandu, Nepal
- Next-Generation BioGreen 21 Program, Rural Development Administration, Republic of Korea [PJ008154, PJ008321]
- National Natural Science Foundation of China [30870450]
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Ophiocordyceps sinensis (syn. Cordyceps sinensis) is a highly valued medicinal fungus. This entomopathogen has a limited distribution, has been overharvested in the wild, and its stromata have not been artificially cultivated. Another entomopathogenic fungus, Cordyceps militaris (commonly known as orange caterpillar fungus), has chemical capacities similar to those of O. sinensis, but unlike O. sinensis, its stromata can be easily cultivated. Consequently, C. militaris is being studied as an alternative to O. sinensis, and the large-scale production of stromata is receiving substantial attention. Significant research has been conducted on the genetic resources, nutritional and environmental requirements, mating behavior, and biochemical and pharmacological properties of C. militaris. The complete genome of C. militaris has recently been sequenced. This fungus has been the subject of many reviews, but few have focused on its biology. The current paper reviews the biological aspects of the fungus including host range, mating system, cytology and genetics, insect- and non-insect nutritional requirements, environmental influence on stroma development, and commercial development.
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