4.1 Article

Swim-up procedure selects spermatozoa with longer telomere length

Publisher

ELSEVIER
DOI: 10.1016/j.mrfmmm.2010.03.003

Keywords

Sperm; Telomeres; Swim-up; DNA fragmentation; Sperm Chromatin Dispersion test; SCD

Funding

  1. Consejo de Seguridad Nuclear from Spain

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Telomere length and sperm DNA fragmentation were determined in sperm samples from 27 patients, using a quantitative PCR (Q-PCR) assay and the Sperm Chromatin Dispersion (SCD) test, respectively. Comparisons of the samples before and after swim-up processing demonstrated that this procedure selects a sperm population with longer average telomere size and lower frequency of sperm cells with fragmented DNA. (C) 2010 Elsevier B V All rights reserved.

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