Journal
MUSCLE & NERVE
Volume 46, Issue 3, Pages 313-331Publisher
WILEY
DOI: 10.1002/mus.23282
Keywords
amyotrophic lateral sclerosis; mechanical insufflation-exsufflation; noninvasive ventilation; practical guide; respiratory therapy
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Respiratory complications are a common cause of morbidity and mortality in amyotrophic lateral sclerosis (ALS). Treatment of respiratory insufficiency with noninvasive ventilation (NIV) improves ALS patients' quality of life and survival. Evidence-based practice guidelines for the management of ALS patients recommend treatment of respiratory insufficiency with NIV as well as consideration of insufflation/exsufflation to improve clearance of airway secretions. Despite these recommendations respiratory therapies remain underused. In this review we provide a practical guide for the clinician to prescribe and manage respiratory therapies for the patient with ALS. Muscle Nerve 46: 313331, 2012
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