Journal
MUSCLE & NERVE
Volume 42, Issue 1, Pages 140-143Publisher
JOHN WILEY & SONS INC
DOI: 10.1002/mus.21638
Keywords
artificial hip joint; biopsy; metal intoxication; polyneuropathy; toxic neuropathy
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Although metal intoxication after arthroplasty causes various symptoms, polyneuropathy has never been the focus of clinical investigation. We report the case of a 56-year-old woman with metal neuropathy. She had metallosis after hip arthroplasty with a cobalt-chromium alloy prosthesis. She developed progressive sensory disturbance, hearing loss, and hypothyroidism. Sural nerve biopsy indicated axonopathy. After exchange arthroplasty, blood levels of cobalt and chromium decreased, and her symptoms improved. Cobalt or chromium can cause axonopathy. Muscle Nerve 42: 140-143, 2010
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