Journal
MUSCLE & NERVE
Volume 39, Issue 1, Pages 87-90Publisher
WILEY
DOI: 10.1002/mus.21197
Keywords
neuromyelitis optica; autoantibodies; myasthenia gravis; aquaporin-4; water channel; acetylcholine receptor; multiple sclerosis; muscle; neural
Categories
Funding
- Ralph Wilson Medical Research Foundation
- Gauthy Jackson Charitable Foundation
Ask authors/readers for more resources
We systematically evaluated the frequency of neurological disorders and muscle and neural autoantibodies in 177 patients with neuromyelitis optica (NMO) and in 250 control subjects (173 healthy; 77 multiple sclerosis, MS, patients). An excess of myasthenia gravis (MG, 2%), and muscle-type acetylcholine receptor antibody (11%) was detected among NMO patients. The presence of neural or muscle autoantibodies was more common in NMO patients (34%) than in MS patients or healthy controls (7%), P < 0.0001. The coexistence of NMO and MG should be considered in atypical or refractory presentations of either disorder.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available