4.4 Article

MOTOR UNIT CHANGES IN THORACIC PARASPINAL MUSCLES IN AMYOTROPHIC LATERAL SCLEROSIS

Journal

MUSCLE & NERVE
Volume 39, Issue 1, Pages 83-86

Publisher

JOHN WILEY & SONS INC
DOI: 10.1002/mus.21202

Keywords

amyotrophic lateral sclerosis; cervical paraspinal muscles; electromyography; motor units; thoracic paraspinal muscles

Funding

  1. Fundacao para a Ciencia e Tecnologia [SFRH/BD/30714/2006]

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In 38 amyotrophic lateral sclerosis (ALS) patients and 28 controls, we performed motor unit potential (MUP) analysis in the C-6 and T-5 paraspinal and biceps muscles. In ALS cases, we found similar abnormalities in MUPs in paraspinal and limb muscles. Fasciculation potentials (FPs) were more frequent in biceps than in paraspinal muscles, but fibrillation potentials and positive sharp waves (fibs-sw) were equally frequent in all three muscles. These results confirm the value of paraspinal MUP analysis in the diagnosis of ALS.

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