Journal
MUSCLE & NERVE
Volume 39, Issue 5, Pages 647-651Publisher
JOHN WILEY & SONS INC
DOI: 10.1002/mus.21212
Keywords
BMI; body composition; dual-energy X-ray absorptiometry; fat tissue mass; Duchenne muscular dystrophy; lean tissue mass; muscle strength
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Funding
- National Institute on Disability and Rehabilitation Research [H133B031118]
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The purpose of this study was to assess regional body composition and its correlation with regional strength in Duchenne muscular dystrophy (DMD) subjects and able-bodied controls. Regional dual-energy X-ray absorptiometry (DEXA) measurements and isometric strength were obtained for 23 DMD subjects and 23 control subjects. DMD subjects showed a decreased regional lean mass (P < 0.001). The correlation between regional strength and regional lean mass was stronger for controls than for DMD subjects. DMD subjects had decreased regional lean mass, increased regional fat mass, and decreased strength.
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