Journal
MUSCLE & NERVE
Volume 40, Issue 2, Pages 294-296Publisher
WILEY
DOI: 10.1002/mus.21425
Keywords
Wilson's disease; sensory motor neuropathy; copper deficiency; zinc acetate; chelator
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Copper deficiency may cause myeloneuropathy or progressive limb weakness. By contrast, Wilson's disease (WD) is characterized by progressive copper accumulation with hepatic and neurological impairment and requires life-long treatment with zinc and/or chelator agents. We report a WD patient who developed axonal sensory motor neuropathy in the context of copper deficiency due to his treatment with zinc and chelators. Exhaustive testing for other etiologies was negative. After treatment adjustment, only mild clinical improvement was noted during long-term follow-up. Muscle Nerve 40: 294-296, 2009
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