Journal
MUSCLE & NERVE
Volume 40, Issue 4, Pages 643-647Publisher
JOHN WILEY & SONS INC
DOI: 10.1002/mus.21353
Keywords
chronic graft-versus-host disease; dermatomyositis; hematopoietic stem cell transplantation; myositis; perifascicular atrophy
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Myositis is a rare complication of chronic graft-versus-host disease (cGVHD) following hematopoietic stem cell transplantation (HSCT). Almost all such patients have been reported to have polymyositis (PM). We describe clinical, pathologic, and molecular studies of 3 patients with cGVHD following allogeneic HSCT who developed myopathy. In each case, perifascicular atrophy, the pathognomonic histologic feature of dermatomyositis (DM), was observed. Muscle Nerve 40: 643-647, 2009
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