Journal
MULTIPLE SCLEROSIS JOURNAL
Volume 18, Issue 5, Pages 662-668Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/1352458511424422
Keywords
cost of illness; Czech Republic; direct costs; disability; indirect costs; multiple sclerosis
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Funding
- Czech Ministry of Education [MSM 0021620849]
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Background: Information about cost of multiple sclerosis (MS) is available from a number of European countries, but no data from the Czech Republic have been published so far. Objective: The objective of this study was to establish the cost of MS in the Czech Republic, overall and by level of disease severity. Methods: Data on demographics, disease history, resource consumption and production losses were collected from 909 patients recruited in 7 MS centres in the Czech Republic. Annual costs were estimated in the societal perspective, using 2007 unit costs. To evaluate the relationship between disability and costs, patients were stratified into those with mild (67%), moderate (27%) and severe (10%) disability using the Expanded Disability Status Scale. Results: Mean total annual costs per patient were (sic)12,272, of which 51% were direct medical costs, 4% direct non-medical costs and 45% indirect costs. The average annual costs in patients with mild, moderate and severe disability amounted to (sic)9905, (sic)14,064 and (sic)22,880, respectively. Conclusion: The total costs of MS in the Czech Republic are estimated at (sic)208.6 million per year. Consistent with other studies, the costs increase significantly with the severity of MS.
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