Fe3O4 nano-particles supported on cellulose as an efficient catalyst for the synthesis of pyrimido[4,5-b]quinolines in water

Fe3O4 nano-particles supported on cellulose were provided as a catalyst via in situ preparation of Fe3O4 nano-particles and their deposition on cellulose. This catalyst, after characterization with TEM and FAAS analyses, was used as an efficient heterogeneous catalyst for the synthesis of pyrimido[4,5-b]quinolines. Three-component reaction of various aromatic aldehydes, 6-amino-1,3-dimethyluracil, and dimedone or 1,3-cyclohexadione in H2O as a green solvent under reflux conditions after 2 h gave pyrimido[4,5-b]quinolines in high yields. Fe3O4 supported on cellulose was recycled in the reaction for 5 cycles without significant decrease in activity.