Journal
MONATSHEFTE FUR CHEMIE
Volume 144, Issue 11, Pages 1725-1733Publisher
SPRINGER WIEN
DOI: 10.1007/s00706-013-1034-3
Keywords
Schiff bases; Carbonyl compounds; Thiosemicarbazones; Thiazoles
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New series of Schiff's bases, hydrazones, thiosemicarbazones, thiazoles, and thiocarbohydrazones of 5-fluoroisatin were synthesized by the reaction of 5-fluoroisatin with primary amines, hydrazine hydrate, and thiocarbohydrazides. Thiosemicarbazones were prepared by reacting hydrazone derivatives with isothiocyanates. Upon treatment of thiosemicarbazone derivatives with chloroacetone, the thiazole derivatives were obtained. Some of the prepared compounds exhibited antiviral activity.
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