4.2 Article

Synthesis of a new class of tetronic acid derivatives: a one-pot three-component condensation reaction between isoquinoline or pyridine and dialkyl acetylenedicarboxylate with tetronic acid

Journal

MONATSHEFTE FUR CHEMIE
Volume 144, Issue 7, Pages 1051-1055

Publisher

SPRINGER WIEN
DOI: 10.1007/s00706-012-0919-x

Keywords

Isoquinoline; Pyridine; Quinoline; Tetronic acid; Multi-component reactions

Funding

  1. Research Council of Tehran University

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Reaction of the zwitterions generated from isoquinoline or pyridine and dialkyl acetylenedicarboxylate with tetronic acid leads to 1,2-dihydroisoquinoline or 1,2-dihydropyridine tetronic acid derivatives without using any catalyst or activation at room temperature.

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