Journal
MONATSHEFTE FUR CHEMIE
Volume 143, Issue 5, Pages 835-839Publisher
SPRINGER WIEN
DOI: 10.1007/s00706-011-0648-6
Keywords
2,3-Dihydroquinazolin-4(1H)-ones; Metal benzenesulfonate; Multicomponent reaction; Isatoic anhydride; Heterocycle
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Funding
- Committee of Science and Technology of Liaoning Province of China [20091001]
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Copper benzenesulfonate was found to be an effective catalyst for one-pot three-component cyclocondensation of isatoic anhydride, aromatic aldehydes, and ammonium salts or primary amines in aqueous solution to afford the corresponding mono- and disubstituted 2,3-dihydroquinazolin-4(1H)-ones in good yields. The catalyst is reusable and could be recycled for several times without distinct decrease in its efficiency.
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