Journal
MONATSHEFTE FUR CHEMIE
Volume 141, Issue 8, Pages 877-881Publisher
SPRINGER WIEN
DOI: 10.1007/s00706-010-0341-1
Keywords
Quinazolinone; Heterocycle; Iodine; Multicomponent reaction; Aldehyde; Amine
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Funding
- Research Council of Shahid Beheshti University
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An effective one-pot three-component route to 4(3H)-quinazolinones from commercially available starting materials is reported. Thus, isatoic anhydride reacted with ammonium acetate or primary amines and aldehydes in the presence of iodine to produce the corresponding quinazolinone derivatives in moderate to good yields.
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