Journal
MONATSHEFTE FUR CHEMIE
Volume 139, Issue 3, Pages 267-270Publisher
SPRINGER WIEN
DOI: 10.1007/s00706-007-0776-1
Keywords
Mitsunobu's reagent; carbon dioxide; amines; substituted ureas
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A Mitsunobu-based protocol has been developed for the synthesis of symmetrically and unsymmetrically substituted ureas from a variety of primary and secondary amines using gaseous carbon dioxide, in good to excellent yields. This protocol is mild and efficient compared to other reported methods.
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