Journal
MONATSHEFTE FUR CHEMIE
Volume 139, Issue 5, Pages 579-585Publisher
SPRINGER WIEN
DOI: 10.1007/s00706-007-0793-0
Keywords
pyrimidines; thienopyrimidine; thiopyranopyrimidine; antiinflammatory activity
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In continuation to our search for new heterocyclic systems based antiinflammatories, the suggestion and synthesis of some pyrimidines, thienopyrimidines, and their derivatives, were herein realized. The pharmacological screening showed that many of these compounds have good antiinflammatory activity. The structure assignments of the new compounds are based on chemical and spectroscopic evidence. The detailed synthesis, spectroscopic data, and pharmacological properties are reported.
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