4.6 Review

Gold Catalyzed Multicomponent Reactions beyond A3 Coupling

Journal

MOLECULES
Volume 23, Issue 9, Pages -

Publisher

MDPI
DOI: 10.3390/molecules23092255

Keywords

beta-alkoxyketones; butenolides; catalysis; ethers; gold; 3,4-dihydropyrimidin-2(1H)-ones; 1,4-dihydropyridines; multicomponent reactions; oxazoles; pyridines; spirocycles; thiazolo-quinolines

Funding

  1. Ministerio de Economia y Competitividad (MINECO/FEDER) [CTQ2016-75816-C2-1-P, CTQ2017-88091-P]
  2. Gobierno de Aragon-Fondo Social Europeo [E07_17R]

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The preparation of complex architectures has inspired the search for new methods and new processes in organic synthesis. Multicomponent reactions have become an interesting approach to achieve such molecular diversity and complexity. This review intends to illustrate important gold-catalyzed examples for the past ten years leading to interesting skeletons involved in biologically active compounds.

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