Journal
MOLECULES
Volume 19, Issue 10, Pages 16458-16476Publisher
MDPI
DOI: 10.3390/molecules191016458
Keywords
caffeic acid phenethyl ester; chemical structure; biological; synthetic method; structural modification
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Caffeic acid phenethyl ester (CAPE), as one of the main active ingredients of the natural product propolis, shows the unique biological activities such as anti-tumor, anti-oxidation, anti-inflammatory, immune regulation, and so on. These have attracted the attention of many researchers to explore the compound with potent biological activities. This review aims to summarize its bioactivities, synthetic methods and derivatives, which will be helpful for further study and development of CAPE and its derivatives.
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