Journal
MOLECULES
Volume 19, Issue 9, Pages 14919-14947Publisher
MDPI
DOI: 10.3390/molecules190914919
Keywords
resveratrol; exercise; mitochondria; reactive oxygen species; nitric oxide
Funding
- Diabetes Foundation of Manitoba
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Regular exercise contributes to healthy aging and the prevention of chronic disease. Recent research has focused on the development of molecules, such as resveratrol, that activate similar metabolic and stress response pathways as exercise training. In this review, we describe the effects of exercise training and resveratrol on some of the organs and tissues that act in concert to transport oxygen throughout the body. In particular, we focus on animal studies that investigate the molecular signaling pathways induced by these interventions. We also compare and contrast the effects of exercise and resveratrol in diseased states.
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