Journal
MOLECULES
Volume 18, Issue 7, Pages 8160-8167Publisher
MDPI AG
DOI: 10.3390/molecules18078160
Keywords
flexibilisquinone; cultured soft coral; Sinularia flexibilis; anti-inflammatory; iNOS; COX-2
Funding
- Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University [00C-0302-05]
- National Dong Hwa University
- National Museum of Marine Biology and Aquarium
- National Science Council, Taiwan [NSC 100-2320-B-110-001-MY2, 102-2325-B-291-001, 101-2320-B-291-001-MY3]
Ask authors/readers for more resources
A new quinone derivative, flexibilisquinone (1), was isolated from the cultured soft coral Sinularia flexibilis, originally distributed in the waters of Taiwan. The structure of quinone 1 was established by extensive spectroscopic methods, particularly 1D and 2D NMR experiments. In the in vitro anti-inflammatory effects test, quinone 1 was found to significantly inhibit the accumulation of the pro-inflammatory iNOS and COX-2 proteins of the LPS-stimulated RAW264.7 macrophage cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
