Journal
MOLECULES
Volume 18, Issue 11, Pages 13623-13635Publisher
MDPI
DOI: 10.3390/molecules181113623
Keywords
benzofuran; benzothiazole; beta-amino acid ester; anti-TMV activity
Funding
- National Natural Science Foundation of China [2132003, 20872021]
Ask authors/readers for more resources
Starting from benzofuran-2-methanal, 6-substituted benzothiazole-2-amines and malonic esters, sixteen title compounds were designed and synthesized seeking to introduce anti-TMV activity. The structures of the newly synthesized compounds were confirmed by H-1-NMR, C-13-NMR, IR spectra, and MS (HREI) analysis. The bioassays identified some of these new compounds as having moderate to good anti-TMV activity. The compounds 5i and 5m have good antiviral activity against TMV with a curative rate of 52.23% and 54.41%, respectively, at a concentration of 0.5 mg/mL.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available