4.6 Article

One-Pot Synthesis of 2-Phenylimidazo[1,2-α]pyridines from Acetophenone, [Bmim]Br3 and 2-Aminopyridine under Solvent-Free Conditions

Journal

MOLECULES
Volume 17, Issue 11, Pages 13368-13375

Publisher

MDPI
DOI: 10.3390/molecules171113368

Keywords

imidazo[1,2-alpha]pyridine; aromatics; 2-aminopyridine; [Bmim]Br-3

Funding

  1. NSFC [21262002]
  2. Science Foundation of JiangXi Province [2010GZH0003\20113BCB24011]
  3. Science and Technology Foundation of the Education Department of JiangXi Province [GJJ12370]

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One-pot synthesis of 2-phenylimidazo[1,2-alpha]pyridines from acetophenone, [Bmim]Br-3 and 2-aminopyridine under solvent-free conditions in the presence of Na2CO3, gave the corresponding 2-phenylimidazo[1,2-alpha]pyridines in excellent yields ranging from 72% to 89%.

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