4.6 Article

A New Norisoprenoid and Other Compounds from Fuzhuan Brick Tea

Journal

MOLECULES
Volume 17, Issue 3, Pages 3539-3546

Publisher

MDPI
DOI: 10.3390/molecules17033539

Keywords

Fuzhuan brick tea; norisoprenoid; 3R,9R-oxido-5-megastigmene; antimicrobial activity; enteric pathogenic microorganisms

Funding

  1. Ministry of Agriculture & Ministry of Finance, People's Republic of China
  2. Natural Science Foundation of Anhui Province [10040606Q19]
  3. National Natural Science Foundation of China [31101335, 21172224]

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Fuzhuan brick tea, a kind of dark tea consumed mainly in the border regions of Southwestern and Northwestern China since the 1860s, is produced from the leaves of Camellia sinensis var. sinensis by microbial fermentation. From this special fermented tea, a new norisoprenoid, 3R,9R-oxido-5-megastigmene, was isolated, together with a-linolenic acid, strictin, isovitexin, astragalin, (+)-catechin, (-)-epicatechin, (-)-epicatechin gallate, (+)-gallocatechin, (-)-epigallocatechin, (-)-epigallocatechin gallate and gallic acid. The structures of the compounds were identified by spectroscopic means. The new compound didn't show any inhibition activity against the tested enteric pathogenic microorganisms at a concentration of 800 mu g/mL by the hole plate diffusion method.

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