Journal
MOLECULES
Volume 16, Issue 4, Pages 3444-3455Publisher
MDPI
DOI: 10.3390/molecules16043444
Keywords
propolis; antioxidant activity; phenolics; natural antioxidants
Funding
- national comprehensive technology platforms for innovative drug RD [2009ZX09301-007]
- Shanghai Key Laboratory of Complex Prescription (Shanghai University of Traditional Chinese Medicine) [10DZ2270900]
- Shanghai Jiao Tong University [A10CX60]
- Shanghai Jiao Tong University Undergraduate Student [IPP1093]
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The antioxidant activities of the chloroform, ethyl acetate and n-butanol extract fractions from propolis collected in Anhui, China were evaluated in this study. The ethyl acetate fraction contained the highest amount of total phenolics and total flavonoids, and showed the greatest 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) radical scavenging capacities and Ferric Reducing/Antioxidant Power (FRAP). The antioxidant activity of twenty-two compounds isolated from the ethyl acetate fraction was also evaluated using the above-mentioned three assays. The results indicated that phenolics contributed to the antioxidant activity of propolis collected in Anhui, China. Therefore, propolis collected in Anhui, China and its phenolics might be used as a natural antioxidant.
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