Journal
MOLECULES
Volume 16, Issue 3, Pages 2443-2466Publisher
MDPI AG
DOI: 10.3390/molecules16032443
Keywords
triterpene; allobetulin; rearrangement; biological activity
Funding
- University of Leuven
- F.W.O-Vlaanderen
- I.U.A.P.
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This review covers the chemistry of allobetulin analogs, including their formation by rearrangement from betulin derivatives, their further derivatisation, their fusion with heterocyclic rings, and any further rearrangements of allobetulin compounds including ring opening, ring contraction and ring expansion reactions. In the last part, the most important biological activities of allobetulin derivatives are listed. One hundred and fifteen references are cited and the relevant literature is covered, starting in 1922 up to the end of 2010.
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