4.6 Article

Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines

Journal

MOLECULES
Volume 15, Issue 5, Pages 2949-2961

Publisher

MDPI
DOI: 10.3390/molecules15052949

Keywords

quinazoline; Suzuki-Miyaura reaction; microwaves; S(RN)1

Funding

  1. CNRS
  2. University of Aix-Marseille II

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New diarylquinazolines displaying pharmaceutical potential were synthesized in high yields from 4,7-dichloro-2-(2-methylprop-1-enyl)-6-nitroquinazoline by using microwave-promoted regioselective Suzuki-Miyaura cross-coupling reactions.

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