4.6 Review

Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides

Journal

MOLECULES
Volume 15, Issue 9, Pages 6638-6677

Publisher

MDPI
DOI: 10.3390/molecules15096638

Keywords

ring-closing metathesis; peptides; structure; pharmacological properties

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Applications of ring-closing alkene metathesis (RCM) in acyclic alpha- and beta-peptides and closely related systems are reviewed, with a special emphasis on the structural and pharmacological effects of cyclization by RCM.

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