Journal
MOLECULES
Volume 14, Issue 9, Pages 3153-3160Publisher
MDPI
DOI: 10.3390/molecules14093153
Keywords
Suzuki reaction; ligand-free; aqueous phase; 2,3,5-trichloropyridine; 3,5-dichloro-2-arylpyridines
Funding
- Nature Science Foundation of Zhejiang Province, China [Y407350]
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A highly efficient palladium acetate-catalyzed ligand-free Suzuki reaction of 2,3,5-trichloropyridine with arylboronic acids in aqueous phase was developed. High yields of 3,5-dichloro-2-arylpyridines, a simple Pd source, absence of ligands, and environmentally benign as well as mild reaction conditions are important features of this method.
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