Journal
MOLECULES
Volume 14, Issue 1, Pages 474-479Publisher
MDPI
DOI: 10.3390/molecules14010474
Keywords
Solvent-free reaction; Barbituric acid; Pyrimidinediones; Heterocyclic compounds; Ball-milling
Funding
- Iran University of Science and Technology (IUST)
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Solvent-free synthesis of pyrano[2,3-d]pyrimidine-2,4(1H,3H)-diones by ball-milling and without any catalyst is described. This method provides several advantages such as being environmentally friendly, using a simple workup procedure, and affording high yields.
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