Journal
MOLECULES
Volume 14, Issue 12, Pages 5203-5215Publisher
MDPI
DOI: 10.3390/molecules14125203
Keywords
hydrazones; pyridinium salts; synthesis; antimicrobial activity
Funding
- Ege University Scientific Research Project Council [07/ECZ/007]
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Some substituted benzylidenehydrazinylpyridinium derivatives bearing benzyl, ethylphenyl and propylphenyl groups on the pyridinium nitrogen were synthesized and screened for possible antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans using the microdilution method. Antimicrobial test results indicated that compounds containing a 3-phenylpropyl chain displayed the highest antimicrobial activity against Staphylococcus aureus and the compound 3d was the most active in the series against all tested bacteria and fungi strains.
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