Journal
MOLECULES
Volume 15, Issue 1, Pages 12-26Publisher
MDPI
DOI: 10.3390/molecules15010012
Keywords
carbohydrates; furan derivatives; cytotoxic activity; anti-tumor; apoptosis
Funding
- Fundacao de Amparo a Pesquisa do Estado de Minas Gerais (FAPEMIG)
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
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In our search for new anticancer therapies, some compounds synthesized in our lab were selected and their potential cytotoxic activity was evaluated in vitro against two cancer cells lines including a solid tumor (UACC-62, melanoma) and a human lymphoma (JURKAT). Compounds showing cytotoxic activity were subjected to an apoptosis assay. Two compounds showed promising results.
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