Related references
Note: Only part of the references are listed.Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome
Omar S. Khwaja et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Stem Cells as a Good Tool to Investigate Dysregulated Biological Systems in Autism Spectrum Disorders
Karina Griesi-Oliveira et al.
AUTISM RESEARCH (2013)
Developmental delays and reduced pup ultrasonic vocalizations but normal sociability in mice lacking the postsynaptic cell adhesion protein neuroligin2
Markus Woehr et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
Monogenic mouse models of social dysfunction: Implications for autism
D. Oddi et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
Hyperforin modulates dendritic spine morphology in hippocampal pyramidal neurons by activating Ca2+-permeable TRPC6 channels
Kristina Leuner et al.
HIPPOCAMPUS (2013)
Transcriptome Comparison of Human Neurons Generated Using Induced Pluripotent Stem Cells Derived from Dental Pulp and Skin Fibroblasts
Jian Chen et al.
PLOS ONE (2013)
The Expanding Role of MBD Genes in Autism: Identification of a MECP2 Duplication and Novel Alterations in MBD5, MBD6, and SETDB1
Holly N. Cukier et al.
AUTISM RESEARCH (2012)
Sequencing Chromosomal Abnormalities Reveals Neurodevelopmental Loci that Confer Risk across Diagnostic Boundaries
Michael E. Talkowski et al.
CELL (2012)
Modeling neurodevelopmental disorders using human neurons
Thanathom Chailangkarn et al.
CURRENT OPINION IN NEUROBIOLOGY (2012)
Autistic-like behaviour in Scn1a+/- mice and rescue by enhanced GABA-mediated neurotransmission
Sung Han et al.
NATURE (2012)
Patterns and rates of exonic de novo mutations in autism spectrum disorders
Benjamin M. Neale et al.
NATURE (2012)
De novo mutations revealed by whole-exome sequencing are strongly associated with autism
Stephan J. Sanders et al.
NATURE (2012)
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
Brian J. O'Roak et al.
NATURE (2012)
De Novo Gene Disruptions in Children on the Autistic Spectrum
Ivan Iossifov et al.
NEURON (2012)
AutismKB: an evidence-based knowledgebase of autism genetics
Li-Ming Xu et al.
NUCLEIC ACIDS RESEARCH (2012)
Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice
Wei Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Genetic and Functional Analyses of SHANK2 Mutations Suggest a Multiple Hit Model of Autism Spectrum Disorders
Claire S. Leblond et al.
PLOS GENETICS (2012)
A MECP2 missense mutation within the MBD domain in a Brazilian male with autistic disorder
Mario Campos Junior et al.
BRAIN & DEVELOPMENT (2011)
Feeder-Free Derivation of Induced Pluripotent Stem Cells From Human Immature Dental Pulp Stem Cells
Patricia C. B. Beltrao-Braga et al.
CELL TRANSPLANTATION (2011)
Disentangling the Myriad Genomics of Complex Disorders, Specifically Focusing on Autism, Epilepsy, and Schizophrenia
M. Poot et al.
CYTOGENETIC AND GENOME RESEARCH (2011)
Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises
Maria C. Marchetto et al.
HUMAN MOLECULAR GENETICS (2011)
Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia
A. Piton et al.
MOLECULAR PSYCHIATRY (2011)
Transcriptomic analysis of autistic brain reveals convergent molecular pathology
Irina Voineagu et al.
NATURE (2011)
The conundrums of understanding genetic risks for autism spectrum disorders
Matthew W. State et al.
NATURE NEUROSCIENCE (2011)
Interaction between FEZ1 and DISC1 in Regulation of Neuronal Development and Risk for Schizophrenia
Eunchai Kang et al.
NEURON (2011)
Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism
Stephan J. Sanders et al.
NEURON (2011)
Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions
Guo-li Ming et al.
NEURON (2011)
Evidence for a supportive role of classical transient receptor potential 6 (TRPC6) in the exploration behavior of mice
Daniel Beis et al.
PHYSIOLOGY & BEHAVIOR (2011)
Autism-Associated Gene Expression in Peripheral Leucocytes Commonly Observed between Subjects with Autism and Healthy Women Having Autistic Children
Yuki Kuwano et al.
PLOS ONE (2011)
A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells
Maria C. N. Marchetto et al.
CELL (2010)
Functional Annotation of Genes Overlapping Copy Number Variants in Autistic Patients: Focus on Axon Pathfinding
Silvia Sbacchi et al.
CURRENT GENOMICS (2010)
Targeting CREB signalling in neurogenesis
Sebastian Dworkin et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2010)
Delayed Stabilization of Dendritic Spines in Fragile X Mice
Alberto Cruz-Martin et al.
JOURNAL OF NEUROSCIENCE (2010)
Simple 2,4-Diacylphloroglucinols as Classic Transient Receptor Potential-6 Activators-Identification of a Novel Pharmacophore
K. Leuner et al.
MOLECULAR PHARMACOLOGY (2010)
L1 retrotransposition in neurons is modulated by MeCP2
Alysson R. Muotri et al.
NATURE (2010)
Behavioural phenotyping assays for mouse models of autism
Jill L. Silverman et al.
NATURE REVIEWS NEUROSCIENCE (2010)
Novel variants identified in methyl-CpG-binding domain genes in autistic individuals
Holly N. Cukier et al.
NEUROGENETICS (2010)
Disruption of CNTNAP2 and additional structural genome changes in a boy with speech delay and autism spectrum disorder
Martin Poot et al.
NEUROGENETICS (2010)
The Simons Simplex Collection: A Resource for Identification of Autism Genetic Risk Factors
Gerald D. Fischbach et al.
NEURON (2010)
Fragile X and autism: Intertwined at the molecular level leading to targeted treatments
Randi Hagerman et al.
MOLECULAR AUTISM (2010)
Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication
Ozlem Bozdagi et al.
MOLECULAR AUTISM (2010)
Human Dental Pulp Stem Cells: From Biology to Clinical Applications
Riccardo d'Aquino et al.
JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION (2009)
Modulation of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental retardation and autism
Christopher A. Chapleau et al.
JOURNAL OF NEURODEVELOPMENTAL DISORDERS (2009)
DISC1 Regulates New Neuron Development in the Adult Brain via Modulation of AKT-mTOR Signaling through KIAA1212
Ju Young Kim et al.
NEURON (2009)
Functional roles of TRPC channels in the developing brain
Yilin Tai et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2009)
Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice
Daniela Tropea et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Structural variation of chromosomes in autism spectrum disorder
Christian R. Marshall et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
Specific TRPC6 Channel Activation, a Novel Approach to Stimulate Keratinocyte Differentiation
Margarethe Mueller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
TRPC6 channels promote dendritic growth via the CaMKIV-CREB pathway
Yilin Tai et al.
JOURNAL OF CELL SCIENCE (2008)
Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development
Chad M. McCall et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Critical role of TRPC6 channels in the formation of excitatory synapses
Jian Zhou et al.
NATURE NEUROSCIENCE (2008)
MeCP2, a key contributor to neurological disease, activates and represses transcription
Maria Chahrour et al.
SCIENCE (2008)
Hyperforin -: a key constituent of St. John's wort specifically activates TRPC6 channels
Kristina Leuner et al.
FASEB JOURNAL (2007)
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
Kazutoshi Takahashi et al.
CELL (2007)
Expression of phosphodiesterase 4 is altered in the brains of subjects with autism
Natalie N. Braun et al.
NEUROREPORT (2007)
PennCNV: An integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data
Kai Wang et al.
GENOME RESEARCH (2007)
Disrupted-in-schizophrenia 1 regulates integration of newly generated neurons in the adult brain
Xin Duan et al.
CELL (2007)
TRPC channels promote cerebellar granule neuron survival
Yichang Jia et al.
NATURE NEUROSCIENCE (2007)
QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data
Stefano Colella et al.
NUCLEIC ACIDS RESEARCH (2007)
Molecular mechanisms of autism:: a possible role for Ca2+ signaling
Jocelyn F. Krey et al.
CURRENT OPINION IN NEUROBIOLOGY (2007)
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders
Christelle M. Durand et al.
NATURE GENETICS (2007)
Reduced MeCP2 Expression is Frequent in Autism Frontal Cortex and Correlates with Aberrant MECP2 Promoter Methylation
Raman P. Nagarajan et al.
EPIGENETICS (2006)
CACNA1H mutations in autism spectrum disorders
Igor Splawski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
GABA regulates synaptic integration of newly generated neurons in the adult brain
SY Ge et al.
NATURE (2006)
Increased vascular smooth muscle contractility in TRPC6-/- mice
A Dietrich et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition
AR Muotri et al.
NATURE (2005)
A CACNA1F mutation identified in an X-linked retinal disorder shifts the voltage dependence of Cav1.4 channel activation
A Hemara-Wahanui et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor
Y Li et al.
NATURE (2005)
Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues
XM Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Canonical transient receptor potential 1 plays a role in basic fibroblast growth factor (bFGF)/FGF receptor-1-induced Ca2+ entry and embryonic rat neural stem cell proliferation
AF Pla et al.
JOURNAL OF NEUROSCIENCE (2005)
Multiple pathways regulate MeCP2 expression in normal brain development and exhibit defects in autism-spectrum disorders
RC Samaco et al.
HUMAN MOLECULAR GENETICS (2004)
Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments
R Breitling et al.
FEBS LETTERS (2004)
Cav1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
I Splawski et al.
CELL (2004)
DNA methylation-related chromatin remodeling in activity-dependent Bdnf gene regulation
K Martinowich et al.
SCIENCE (2003)
SHED: Stem cells from human exfoliated deciduous teeth
M Miura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
RA Irizarry et al.
BIOSTATISTICS (2003)
Identification of MeCP2 mutations in a series of females with autistic disorder
RM Carney et al.
PEDIATRIC NEUROLOGY (2003)
Current St. John's wort research from mode of action to clinical efficacy
WE Müller
PHARMACOLOGICAL RESEARCH (2003)
Stem cell properties of human dental pulp stem cells
S Gronthos et al.
JOURNAL OF DENTAL RESEARCH (2002)
Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB
BE Lonze et al.
NEURON (2002)
A Rett syndrome MECP2 mutation that causes mental retardation in men
MT Dotti et al.
NEUROLOGY (2002)
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
Jo Vandesompele et al.
GENOME BIOLOGY (2002)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
Significance analysis of microarrays applied to the ionizing radiation response
VG Tusher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Evidence for a cerebellar role in reduced exploration and stereotyped behavior in autism
K Pierce et al.
BIOLOGICAL PSYCHIATRY (2001)
Isolation and characterization of a novel presenilin binding protein
A Kashiwa et al.
JOURNAL OF NEUROCHEMISTRY (2000)
Share Paper
