Journal
MOLECULAR PLANT PATHOLOGY
Volume 10, Issue 1, Pages 109-113Publisher
WILEY
DOI: 10.1111/j.1364-3703.2008.00513.x
Keywords
-
Categories
Funding
- EPR Aquitaine [20000307004]
- French National Agency for Research [ANR05-BLAN-0302-01]
- Syrian Ministry of Higher Education
- Institut National de la Recherche Agronomique
Ask authors/readers for more resources
The capacity of Lettuce mosaic virus to overcome the lettuce resistance conferred by the mo1(1) and mo1(2) alleles of the gene for eukaryotic translation initiation factor 4E (eIF4E) was analysed using reverse genetics. Mutations in the virus genome-linked protein (VPg) allowed mo1(1) only to be overcome, but mutations in the C-terminal portion of the cylindrical inclusion (CI) protein allowed both alleles to be overcome. Site-directed mutagenesis pinpointed a key role of the amino acid at position 621 in the virulence. This is the first example of the involvement of a potyviral CI protein in the breaking of an eIF4E-mediated resistance.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available